欧美国产精品一区二区网站-青青在线香蕉国产精品-成人黄网站免费app-九九视频在线观看视频

資訊中心NEWS CENTER

在發(fā)展中求生存,不斷完善,以良好信譽(yù)和科學(xué)的管理促進(jìn)企業(yè)迅速發(fā)展

首頁(yè)-技術(shù)文章-微波解決了蛋白質(zhì)研究的極限

企業(yè)新聞 技術(shù)文章

微波解決了蛋白質(zhì)研究的極限

更新時(shí)間:2012-11-16       點(diǎn)擊次數(shù):2125

        one of the greatest advances in solid phase peptide synthesis (SPPS) and proreomics over the past decade is the lise of microwave irradiation to overcome incomplete and slow reactions typical of conventional SPPS and  prorcomic sample preparation.

        Microwave energy has beell applied SlICcessfully in both manual and automated
approaches for enhancing the synthesis of pepridcs and peptidomimctics.

       During the course of conventional pcptide synthesis, the growing peptide chain can form aggregates with itself or neighboring chains, leading to the production of low-quality pcptides. Due to its highly charged resonance structure, the peptide bond will readily absorb microwave energy, which induces molecular morion within the peptide. This random morion can overcome chain aggregation within the peptide, allowing for free access to the N-terminus of the growing peptide chain and resulting in a significant increase in peptide purity.

        Microwave irradiation also call COllsiderably increase the speed at which peptides arc synrhesized. Traditionally, peptide coupling reactions require from 30 minutes up to two hours to reach completion. Microwave energy allows the amino acid coupling to be completed
in just five minutes.

        The Fmoc deprotection reaction can be accelerated in the microwave to decrease
the reaction time from at least 15 minutes to only three minutes. We recendy demonstrated
U. Pept. Sci., 2007) that common side reactions such as racemization and aspartimide formation are easily controllable with optimized methods that can be applied routinely.


 

更多詳情,請(qǐng)培安公司:
:北京: 上海:  成都: 廣州:
: sales@pynnco.comwww.pynnco.com
SCROLL

Copyright©2025 培安有限公司 版權(quán)所有 All Rights Reserved    備案號(hào):京ICP備17026558號(hào)-1    總訪問量:410809

技術(shù)支持:化工儀器網(wǎng)    管理登錄    sitemap.xml

新邵县| 沾益县| 长春市| 涿州市| 乌鲁木齐县| 丰宁| 周口市| 文成县| 榆林市| 甘孜县| 济南市| 遂宁市| 东乡| 仙游县| 徐州市| 工布江达县| 呼和浩特市| 波密县| 宁南县| 恩施市| 诸暨市| 武城县| 武平县| 津南区| 子长县| 南宁市| 遂溪县| 沈阳市| 昔阳县| 桃园县| 甘孜县| 阿合奇县| 江川县| 安福县| 南宫市| 兰溪市| 德江县| 喀喇沁旗| 安岳县| 三江| 沁源县|